Article

Molecular genetic study on <i>HAND2</i> gene promoter in ventricular septal defect

2022-06-28

Abstract excerpt

Ventricular septal defect (VSD), as the most common type of congenital heart disease (CHD), is mainly caused by cardiac dysplasia. Heart and neural crest derivatives expressed 2 ( HAND2) , as a member of the basic helix-loop-Helix (bHLH) gene family, participates in the development of the right heart. And the loss of HAND2 expression in humans is closely connected with ventricular septal defects. However, no studi...

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Literature Corpus work: 88cc113b-f7e3-51b7-9f09-e01815804085
DOI: 10.1101/2022.06.28.22277011

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