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Article

SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes.

Bioinformatics (Oxford, England) - 1 Mar 2016

Steinrücken Matthias, Jewett Ethan M, Song Yun S

Abstract excerpt

MOTIVATION: In the Wright-Fisher diffusion, the transition density function describes the time evolution of the population-wide frequency of an allele. This function has several practical applications in population genetics and computing it for biologically realistic scenarios with selection and demography is an important problem. RESULTS: We develop an efficient method for finding a spectral representation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26556388
DOI: 10.1093/bioinformatics/btv627
PMCID: PMC4907395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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