Article
The multivariate Wright-Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model.
Theoretical population biology - 1 Apr 2016
Hobolth Asger, Siren Jukka
Abstract excerpt
We consider the diffusion approximation of the multivariate Wright-Fisher process with mutation. Analytically tractable formulas for the first-and second-order moments of the allele frequency distribution are derived, and the moments are subsequently used to better understand key population genetics parameters and modeling frameworks. In particular we investigate the behavior of the expected homozygosity (the...
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