Article
Validation of PDE9A Gene Identified in GWAS Showing Strong Association with Milk Production Traits in Chinese Holstein.
International journal of molecular sciences - 5 Nov 2015
Yang Shao-Hua, Bi Xiao-Jun, Xie Yan, Li Cong, Zhang Sheng-Li, Zhang Qin, Sun Dong-Xiao
Abstract excerpt
Phosphodiesterase9A (PDE9A) is a cyclic guanosine monophosphate (cGMP)-specific enzyme widely expressed among the tissues, which is important in activating cGMP-dependent signaling pathways. In our previous genome-wide association study, a single nucleotide polymorphism (SNP) (BTA-55340-no-rs(b)) located in the intron 14 of PDE9A, was found to be significantly associated with protein yield. In addition, we found...
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