Novel Variants in GDF9 Gene Affect Promoter Activity and Litter Size in Mongolia Sheep.

doi:10.3390/genes11040375

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Article

Novel Variants in GDF9 Gene Affect Promoter Activity and Litter Size in Mongolia Sheep.

Genes - 30 Mar 2020

Tong Bin, Wang Jiapeng, Cheng Zixuan, Liu Jiasen, Wu Yiran, Li Yunhua, Bai Chunling, Zhao Suwen, Yu Haiquan, Li Guangpeng

Abstract excerpt

Litter size is an economically important trait in sheep breeding. The objectives of this study were as follows: (1) to ascertain if any of the 19 known variants in the BMPRIB, BMP15, and GDF9 genes are present and associated with the litter size of Mongolia sheep; (2) to identify novel variants in GDF9 and perform association analysis; and (3) to validate the effects of these GDF9 promoter variants on the...

Topics

Animals
Female
Genotype
Growth Differentiation Factor 9
Litter Size
Polymorphism, Single Nucleotide
Pregnancy
Promoter Regions, Genetic
Sheep

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Identifiers

PMID: 32235645
DOI: 10.3390/genes11040375
PMCID: PMC7230991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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