Article
A multiple-SNP approach for genome-wide association study of milk production traits in Chinese Holstein cattle.
PloS one - 1 Jan 2014
Fang Ming, Fu Weixuan, Jiang Dan, Zhang Qin, Sun Dongxiao, Ding Xiangdong, Liu Jianfeng
Abstract excerpt
The multiple-SNP analysis has been studied by many researchers, in which the effects of multiple SNPs are simultaneously estimated and tested in a multiple linear regression. The multiple-SNP association analysis usually has higher power and lower false-positive rate for detecting causative SNP(s) than single marker analysis (SMA). Several methods have been proposed to simultaneously estimate and test multiple...
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