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Genetic effects of PDGFRB and MARCH1 identified in GWAS revealing strong associations with semen production traits in Chinese Holstein bulls.

BMC genetics - 3 Jul 2017

Liu Shuli, Yin Hongwei, Li Cong, Qin Chunhua, Cai Wentao, Cao Mingyue, Zhang Shengli

Abstract excerpt

BACKGROUND: Using a genome-wide association study strategy, our previous study discovered 19 significant single-nucleotide polymorphisms (SNPs) related to semen production traits in Chinese Holstein bulls. Among them, three SNPs were within or close to the phosphodiesterase 3A (PDE3A), membrane associated ring-CH-type finger 1 (MARCH1) and platelet derived growth factor receptor beta (PDGFRB) genes. The present...

Topics

Animals
Cattle
China
Genome-Wide Association Study
Male
Polymorphism, Single Nucleotide
Receptor, Platelet-Derived Growth Factor beta
Semen
Semen Analysis
Sperm Motility
Ubiquitin-Protein Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28673243
DOI: 10.1186/s12863-017-0527-1
PMCID: PMC5496367

Genes

PDGFRB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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