TLR7 Gln11Leu single nucleotide polymorphism and response to treatment with imiquimod in patients with basal cell carcinoma: a pilot study.

doi:10.2217/pgs.15.132

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Article

TLR7 Gln11Leu single nucleotide polymorphism and response to treatment with imiquimod in patients with basal cell carcinoma: a pilot study.

Pharmacogenomics - 1 Nov 2015

Piaserico Stefano, Michelotto Anna, Frigo Anna C, Alaibac Mauro

Abstract excerpt

AIM: The Toll-like receptor 7 (TLR7) agonist, imiquimod, offers a topical and noninvasive therapeutic method for the clinical treatment of superficial basal cell carcinoma (BCC). In this study we explored the relationship between the functional X-linked TLR7 rs179008/Gln11Leu polymorphism and the response to imiquimod in patients with BCC. PATIENTS & METHODS: Thirty-four BCC patients treated with imiquimod were...

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PMID: 26556041
DOI: 10.2217/pgs.15.132

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TLR7

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