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Article

Mechanisms Underlying Imiquimod-Induced Regression of Basal Cell Carcinoma In Vivo

1 Oct 2003

Abstract excerpt

BACKGROUND: Imiquimod is a local immune response modifier that has demonstrated potent antiviral and antitumor activity. It enhances innate and acquired immune responses via endogenous cytokine production and has proven efficacious in clearing superficial basal cell carcinoma (sBCC). OBJECTIVE: To evaluate the mechanisms by which topical imiquimod treatment leads to sBCC clearance in vivo. DESIGN: A pilot,...

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PMID: 14568837
DOI: 10.1001/archderm.139.10.1325

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