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Article

Chronic Obstructive Pulmonary Disease-Related Non-Small-Cell Lung Cancer Exhibits a Low Prevalence of EGFR and ALK Driver Mutations.

PloS one - 1 Jan 2015

Lim Jeong Uk, Yeo Chang Dong, Rhee Chin Kook, Kim Yong Hyun, Park Chan Kwon, Kim Ju Sang, Kim Jin Woo, Lee Sang Haak, Kim Seung Joon, Yoon Hyoung Kyu, Kim Tae-Jung, Lee Kyo Young

Abstract excerpt

Lung cancer and chronic obstructive pulmonary disease (COPD) are two major lung diseases. Epidermal growth factor receptor (EGFR) mutations, v-Ki-ras2 Kirsten rat sarcoma (KRAS) mutations and anaplastic lymphoma kinase (ALK) gene rearrangements represent driver mutations that are frequently assessed on initial evaluation of non-small-cell lung cancer (NSCLC). The present study focused on the expression of driver...

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Source

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Identifiers

PMID: 26555338
DOI: 10.1371/journal.pone.0142306
PMCID: PMC4640806

Genes

EGFR
ALK
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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