Article
Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains.
Oncogene - 25 Jun 1998
Carrère S, Verger A, Flourens A, Stehelin D, Duterque-Coquillaud M
Abstract excerpt
The ets genes family encodes a group of proteins which function as transcription factors under physiological conditions. We report here that the Erg proteins, members of the Ets family, form homo and heterodimeric complexes in vitro. We demonstrate that the Ergp55 protein isoform forms dimers wit...
Topics
- Binding Sites
- Biopolymers
- DNA-Binding Proteins
- Dimerization
- Gene Deletion
- Humans
- Mutation
- Oncogene Proteins
- Protein Binding
- Protein Conformation
- Protein Structure, Tertiary
- Retroviridae Proteins, Oncogenic
- Trans-Activators
- Transcription Factor AP-1
- Transcription Factors
- Transcriptional Activation
- Transcriptional Regulator ERG
- Tumor Cells, Cultured