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Article

Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide.

The Journal of biological chemistry - 1 Dec 2023

Milly Tahmina A, Renshaw Clay P, Tal-Gan Yftah

Abstract excerpt

Bacteria utilize quorum sensing (QS) to coordinate many group behaviors. As such, QS has attracted significant attention as a potential mean to attenuate bacterial infectivity without introducing selective pressure for resistance development. Streptococcus mitis, a human commensal, acts as a genetic diversity reservoir for Streptococcus pneumoniae, a prevalent human pathogen. S. mitis possesses a typical comABCDE...

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Identifiers

PMID: 37951305
DOI: 10.1016/j.jbc.2023.105448
PMCID: PMC10714334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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