Article
Association of ADAM33 polymorphisms with childhood asthma in a northern Chinese population.
Experimental and molecular pathology - 1 Dec 2011
Qu Shuqiang, Sun Donglin, Wang Yan, Zhang Chi, Lv Ying, Yao Li
Abstract excerpt
BACKGROUND: Genetic factors contribute to the increasing incidence of childhood asthma. The ADAM33 (a disintegrin and metalloprotease domain-containing protein 33) gene, discovered through positional cloning, is the first to be associated with asthma and bronchial hyperresponsiveness. This case-control study conducted in a Han Chinese population in northern China compared the genotypes of child asthmatic patients...
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