Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical significance and role of LKB1 in gastric cancer.

Molecular medicine reports - 1 Jan 2016

Jiang Shanshan, Chen Rensheng, Yu Jianan, Li Nianshuang, Ke Rong, Luo Lingyu, Zou Junrong, Zhang Jiangnan, Zhang Kunhe, Lu Nonghua, Huang Deqiang

Abstract excerpt

Liver kinase B1 (LKB1) functions as a tumor suppressor gene, and loss in the expression of LKB1 contributes to human carcinogenesis and tumor progression. The present study investigated the association between LKB1 and gastric cancer. SGC‑7901 gastric cancer cell lines and 63 patients with gastric cancer were examined in the present study, and lentivirus transfection, reverse transription‑quantitative polymerase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinase Kinases
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cell Survival

Share to HEK293 Cells

Share to Hyaluronan Receptors

Share to Protein Serine-Threonine Kinases

Share to Stomach Neoplasms

Source

Identifiers

PMID: 26549522
DOI: 10.3892/mmr.2015.4508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical significance and role of LKB1 in gastric cancer.PMID 26549522Read ↗

Prognostic value of Liver kinase B1 (LKB1) in Gastric Cancers Associates with Tumor Microenvironment ImmunitySemantic proximity Read ↗

Liver kinase B1 (LKB1) in the pathogenesis of epithelial cancers.Semantic proximity Read ↗

The molecular mechanisms that underlie the tumor suppressor function of LKB1.Semantic proximity Read ↗

The role of LKB1 in lung cancerSemantic proximity Read ↗

LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathwaySemantic proximity Read ↗

miR-148-3p inhibits gastric cancer cell malignant phenotypes and chemotherapy resistance by targeting Bcl2.Semantic proximity Read ↗

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinomaSemantic proximity Read ↗

Insights into targeting LKB1 in tumorigenesisSemantic proximity Read ↗

Cytoplasmic liver kinase B1 promotes the growth of human lung adenocarcinoma by enhancing autophagySemantic proximity Read ↗

LKB1 modulates lung cancer differentiation and metastasisSemantic proximity Read ↗

Molecular mechanisms of tumor suppression by LKB1.Semantic proximity Read ↗

LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.