Article
miR-148-3p inhibits gastric cancer cell malignant phenotypes and chemotherapy resistance by targeting Bcl2.
Bioengineered - 1 Dec 2024
Zhang Hongyan, Liang Feng, Wang Fei, Xu Qianru, Qiu Yuxuan, Lu Xin, Jiang Lin, Jian Kaiyu
Abstract excerpt
Gastric cancer (GC) is the fourth most common cancer in the world. This work was designed to explore the biological effects of miR-148-3p on GC. Quantitative reverse transcription-polymerase chain reaction (RT-qPCR) was utilized to analyze the mRNA expression of miR-148-3p in GC cell lines. The mimics and inhibitors of miR-148-3p were carefully transfected into GC cells to up-regulate or down-regulate miR-148-3p...
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