Article

Histone Methyltransferase G9a Promotes Invasion of Non-small Cell Lung Cancer Through Enhancing Focaladhesionkinase Activationvia NF-KB Signaling Pathway

2020-06-17

Abstract excerpt

<h4>Background: </h4> Overexpression of euchromatic histone methyltransferase 2 (EHMT2 or G9a) is frequently found in a number of human cancers. Potential roles of G9a in invasion and metastasis are not well understood in non-small cell lung cancer (NSCLC). Here we investigated the effect and underlying mechanisms of G9a, and therapeutic implications of targeting G9a in the invasion of NSCLC. <h4>Methods: </h4> G9...

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Literature Corpus work: 561d5168-2852-540b-b005-2332e1d308de
DOI: 10.21203/rs.3.rs-35579/v1

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