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Article

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

12 Mar 2012

Abstract excerpt

Breast cancers are highly heterogeneous but can be grouped into subtypes based on several criteria, including level of expression of certain markers. Claudin-low breast cancer (CLBC) is associated with early metastasis and resistance to chemotherapy, while gene profiling indicates it is characterized by the expression of markers of epithelial-mesenchymal transition (EMT) - a phenotypic conversion linked with...

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PMID: 22406531
DOI: 10.1172/jci57349

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