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Article

Alteration in metastasis potential and gene expression in human lung cancer cell lines by ITGB8 silencing.

Anatomical record (Hoboken, N.J. : 2007) - 1 Sept 2012

Xu Zhaoguo, Wu Rong

Abstract excerpt

Lung cancer is the leading cause of cancer death in the world and metastasis is an essential aspect of lung cancer progression. ITGB8 has been implicated in metastasis of human tumors. However, the molecular mechanism by which ITGB8 is involved in tumor metastasis is still unclear. In this study, we compared the gene expression profiles of human lung cancer cell lines A549 and PC9 by ITGB8 gene silencing with...

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Topics

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Share to Cell Line, Tumor
Share to CXCL1 gene
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Integrin beta Chains

Share to Lung Neoplasms

Share to Neoplasm Metastasis

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Source

Identifiers

PMID: 22753015
DOI: 10.1002/ar.22521

Genes

ITGB8
CXCL1
CXCL2
CXCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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