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Article

A haplotype in the 5'-upstream region of the NDUFV2 gene is associated with major depressive disorder in Han Chinese.

Journal of affective disorders - 15 Jan 2016

Zhang Zaifu, Ni Jianliang, Zhang Jiangtao, Tang Wenxin, Li Xiao, Wu Zhiguo, Zhang Chen

Abstract excerpt

BACKGROUND: There is ample evidence supporting the idea that mitochondrial dysfunction and altered expression of complex I subunits play important roles in the pathophysiology of mental disorders. Early literature reports have implicated NDUFV2, a nuclear-encoded mitochondrial complex I subunit gene, in bipolar disorder and schizophrenia. There has been no genetic study to investigate whether there is an...

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Source

Identifiers

PMID: 26544616
DOI: 10.1016/j.jad.2015.10.034

Genes

NDUFV2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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