Article
An association study of the m6A genes with major depressive disorder in Chinese Han population.
Journal of affective disorders - 1 Sept 2015
Du Tingfu, Rao Shuquan, Wu Lin, Ye Ning, Liu Zeyue, Hu Huiling, Xiu Jianbo, Shen Yan, Xu Qi
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is a common, chronic and recurrent mental disease but the precise mechanism behind this disorder remains unknown. FTO is one of the N6-methyladenosine (m6A) modification genes and has recently been found to be associated with depression. N6-methyladenosine (m6A) is the most abundant internal modification on RNA, which is highly enriched within the brain. There are five...
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