Article
Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2003
Washizuka Shinsuke, Kakiuchi Chihiro, Mori Kanako, Kunugi Hiroshi, Tajima Osamu, Akiyama Tsuyoshi, Nanko Shinichiro, Kato Tadafumi
Abstract excerpt
Linkage of bipolar disorder with 18p11 has been replicated by several investigators. A nuclear-encoded mitochondrial complex I subunit gene, NDUFV2, is one of the candidate genes in this locus, since the possible pathophysiological significance of mitochondrial dysfunction in bipolar disorder has been suggested. The objective of our study was to clarify the association between the NDUFV2 gene and bipolar...
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