Article
Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2012
Degenhardt Franziska, Priebe Lutz, Herms Stefan, Mattheisen Manuel, Mühleisen Thomas W, Meier Sandra, Moebus Susanne, Strohmaier Jana, Groß Magdalena, Breuer René, Lange Christoph, Hoffmann Per, Meyer-Lindenberg Andreas, Heinz Andreas, Walter Henrik, Lucae Susanne, Wolf Christiane, Müller-Myhsok Bertram, Holsboer Florian, Maier Wolfgang, Rietschel Marcella, Nöthen Markus M, Cichon Sven
Abstract excerpt
The majority of genetic risk factors for major depressive disorder (MDD) still await identification. Since copy number variants (CNVs) have been implicated in various neuropsychiatric disorders, the question arises as to whether CNVs also play a role in MDD. We performed a genome-wide CNV study using Illumina's SNP array data from 604 MDD patients and 1,643 controls. Putative CNVs were detected with the CNV...
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