Article
Association study on the mitochondrial gene NDUFV2 and bipolar disorder in the Chinese Han population.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2009
Zhang Jing, Li Xingwang, Wang Yang, Ji Jue, Yang Fengping, Feng Guoyin, Wan Peng, Lindpaintner Klaus, He Lin, He Guang
Abstract excerpt
Bipolar disorder is known to be subject to maternal transmission. Mitochondrial DNA has been suggested as playing a role in the illness. NDUFV2, located on 18p11.31-p11.2, encodes an important subunit of mitochondrial NADH (complex I). Previous studies have reported the association of NDUFV2 with bipolar disorder in the Japanese and Caucasian populations. Whether it is also a susceptible gene in the Chinese...
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