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Article

A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo.

PloS one - 1 Jan 2015

Fonseca Simone Aparecida Siqueira, Costas Roberta Montero, Morato-Marques Mariana, Costa Silvia, Alegretti Jose Roberto, Rosenberg Carla, da Motta Eduardo Leme Alves, Serafini Paulo C, Pereira Lygia V

Abstract excerpt

Aneuploid embryos diagnosed by FISH-based preimplantation genetic screening (PGS) have been shown to yield euploid lines of human embryonic stem cells (hESCs) with a relatively high frequency. Given that the diagnostic procedure is usually based on the analysis of 1-2 blastomeres of 5 to 10-cell cleavage-stage embryos, mosaicism has been a likely explanation for the phenomena. However, FISH-based PGS can have a...

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Identifiers

PMID: 26540511
DOI: 10.1371/journal.pone.0140999
PMCID: PMC4634922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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