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Derivation of novel genetically diverse human embryonic stem cell lines.

Stem cells and development - 10 Jun 2012

Stefanova Valentina T, Grifo James A, Hansis Christoph

Abstract excerpt

Human embryonic stem cells (hESCs) have the potential to revolutionize many biomedical fields ranging from basic research to disease modeling, regenerative medicine, drug discovery, and toxicity testing. A multitude of hESC lines have been derived worldwide since the first 5 lines by Thomson et al. 13 years ago, but many of these are poorly characterized, unavailable, or do not represent desired traits, thus...

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PMID: 22204497
DOI: 10.1089/scd.2011.0642

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