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Application of next-generation sequencing for 24-chromosome aneuploidy screening of human preimplantation embryos

15 Jun 2015

Abstract excerpt

BACKGROUND: Aneuploidy is a leading cause of repeat implantation failure and recurrent miscarriages. Preimplantation genetic screening (PGS) enables the assessment of the numeral and structural chromosomal errors of embryos before transfer in patients undergoing in vitro fertilization. Array comparative genomic hybridization (aCGH) has been demonstrated to be an accurate PGS method and in present thought to be...

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PMID: 26085841
DOI: 10.1186/s13039-015-0143-6

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