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Article

An Efficient and Economical Assay to Screen for Triclosan Binding to FabI.

Journal of biomolecular screening - 1 Apr 2016

Demissie Robel D, Kabre Pauline, Tuntland Micheal L, Fung Leslie W-M

Abstract excerpt

Triclosan is an effective inhibitor for enoyl acyl carrier protein reductase (ENR) in fatty acid biosynthesis. Triclosan-resistant mutants of ENR have emerged. Thus, it is important to detect these triclosan-resistant mutations in ENR. Generally, enzyme activity assays on the mutants are used to determine the effect of triclosan on ENR activity. Since the substrates are linked to acyl carrier protein (ACP), the...

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PMID: 26538431
DOI: 10.1177/1087057115615085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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An Efficient and Economical Assay to Screen for Triclosan Binding to FabI.PMID 26538431Read ↗

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