Article
A review of potential pharmacogenetic effects on catecholamine responses.
Drug metabolism reviews - 1 Jan 2015
Ounissi Marwa, Benkirane Aida, Dempsey Eugene, Soares Ricardo, Jullien Vincent, Pons Gérard, Chhun Stéphanie
Abstract excerpt
Considerably, variability in the clinical response to inotropic agents is observed and could be explained partially by the genetic variants, such as single-nucleotide polymorphism (SNP) in genes encoding for enzymes implicated in catecholamines synthesis, metabolism, storage and release or in the signaling pathway. This review highlights the potential effect of pharmacogenetics studies in hemodynamic response and...
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