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Article

Therapeutic relevance of pharmacogenetic factors in cardiovascular medicine.

Pharmacology & therapeutics - 1 Apr 2000

Nakagawa K, Ishizaki T

Abstract excerpt

The variability in the individual response to drugs may be due either to interindividual variations in the pharmacokinetics of the drugs or to the heterogeneity of the mechanism(s) underlying the diseases, or both. In both cases, genetic heterogeneity is involved in the metabolism of cardiovascular drugs and pathogenesis of inherited cardiovascular disorders. Molecular genetic technologies can now provide...

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PMID: 10760544
DOI: 10.1016/s0163-7258(99)00066-2

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