Article
Cardiovascular pharmacogenomics.
Circulation research - 16 Sept 2011
Roden Dan M, Johnson Julie A, Kimmel Stephen E, Krauss Ronald M, Medina Marisa Wong, Shuldiner Alan, Wilke Russell A
Abstract excerpt
Patients vary in their responses to drug therapy, and some of that variability is genetically determined. This review outlines general approaches used to identify genetic variation that influences drug response. Examples from specific therapeutic areas are presented, such as cholesterol management, arrhythmias, heart failure, hypertension, warfarin anticoagulation, and antiplatelet agents. A brief view of...
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