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Article

Anaplastic lymphoma kinase inhibitors as anticancer therapeutics: a patent review

30 Jan 2014

Abstract excerpt

INTRODUCTION: Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase from the insulin receptor superfamily, is implicated in the oncogenesis of numerous cancers including anaplastic large-cell lymphoma, non-small-cell lung cancer, diffuse large B-cell lymphoma, inflammatory myofibroblastic tumors, glioblastoma, as well as neuroblastoma. The root cause for these specific cancers has been identified as...

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PMID: 24476492
DOI: 10.1517/13543776.2014.877890

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