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Article

Anaplastic lymphoma kinase in human cancer.

Critical reviews in oncogenesis - 1 Jan 2012

Schonherr Christina, Hallberg Bengt, Palmer Ruth

Abstract excerpt

The anaplastic lymphoma kinase (ALK) receptor tyrosine kinase is now implicated in a wide range of human cancers. Results from recent clinical trials with ALK inhibitors provide promise for patients harboring oncogenic ALK lesions. This review will discuss our current understanding of ALK in human cancer and the implication of recent results for treatment.

Topics

Anaplastic Lymphoma Kinase
Humans
Mutation
Neoplasms
Protein Kinase Inhibitors
Receptor Protein-Tyrosine Kinases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22471704
DOI: 10.1615/critrevoncog.v17.i2.10

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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