Article
Effects of CYP2C19 allelic variants on inhibition of platelet aggregation and major adverse cardiovascular events in Japanese patients with acute coronary syndrome: The PRASFIT-ACS study.
Journal of cardiology - 1 Jul 2016
Ogawa Hisao, Isshiki Takaaki, Kimura Takeshi, Yokoi Hiroyoshi, Nanto Shinsuke, Takayama Morimasa, Kitagawa Kazuo, Nishikawa Masakatsu, Miyazaki Shunichi, Ikeda Yasuo, Nakamura Masato, Tanaka Yuko, Saito Shigeru
Abstract excerpt
BACKGROUND: We examined the effects of cytochrome P450 2C19 (CYP2C19) polymorphisms on the efficacy and safety of prasugrel and clopidogrel in a post hoc analysis of the PRASugrel compared with clopidogrel For Japanese patIenTs with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) (PRASFIT-ACS) study. METHODS: Japanese ACS patients undergoing PCI were randomized (double-blind) to...
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