Article
Randomized, Double-Blind, Dose-Finding, Phase II Study of Prasugrel in Japanese Patients Undergoing Elective Percutaneous Coronary Intervention.
Journal of atherosclerosis and thrombosis - 1 Jan 2015
Kimura Takeshi, Isshiki Takaaki, Ogawa Hisao, Yokoi Hiroyoshi, Yamaguchi Tetsu, Ikeda Yasuo
Abstract excerpt
AIM: Prasugrel is a novel platelet P2Y12 receptor blocker with a faster onset of action and greater platelet inhibition with less response variability than clopidogrel. Our objective was to determine the optimal prasugrel dose in Japanese patients undergoing elective percutaneous coronary intervention (PCI) with respect to the incidence of bleeding and platelet inhibition. METHODS: A total of 422 patients were...
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