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Article

A critical role for alpha-synuclein in development and function of T lymphocytes.

Immunobiology - 1 Feb 2016

Shameli Afshin, Xiao Wenbin, Zheng Yan, Shyu Susan, Sumodi John, Meyerson Howard J, Harding Clifford V, Maitta Robert W

Abstract excerpt

Alpha-synuclein is highly expressed in the central nervous system and plays an important role in pathogenesis of neurodegenerative disorders such as Parkinson's disease and Lewy body dementia. Previous studies have demonstrated the expression of α-synuclein in hematopoietic elements and peripheral blood mononuclear cells, although its roles in hematopoiesis and adaptive immunity are not studied. Using an...

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Identifiers

PMID: 26517968
DOI: 10.1016/j.imbio.2015.10.002
PMCID: PMC4688145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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