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Article

Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation.

Oxidative medicine and cellular longevity - 1 Jan 2015

Lynch Thomas L, Sivaguru Mayandi, Velayutham Murugesan, Cardounel Arturo J, Michels Michelle, Barefield David, Govindan Suresh, dos Remedios Cristobal, van der Velden Jolanda, Sadayappan Sakthivel

Abstract excerpt

Cardiomyopathies can result from mutations in genes encoding sarcomere proteins including MYBPC3, which encodes cardiac myosin binding protein-C (cMyBP-C). However, whether oxidative stress is augmented due to contractile dysfunction and cardiomyocyte damage in MYBPC3-mutated cardiomyopathies has not been elucidated. To determine whether oxidative stress markers were elevated in MYBPC3-mutated cardiomyopathies, a...

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Identifiers

PMID: 26508994
DOI: 10.1155/2015/424751
PMCID: PMC4609873

Genes

MYBPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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