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Article

Depression, inflammation, and epidermal growth factor receptor (EGFR) status in metastatic non-small cell lung cancer: A pilot study.

Journal of psychosomatic research - 1 Aug 2017

Jacobs Jamie M, Traeger Lara, Eusebio Justin, Simon Naomi M, Sequist Lecia V, Greer Joseph A, Temel Jennifer S, Pirl William F

Abstract excerpt

OBJECTIVE: Patients with stage IV non-small cell lung cancer (NSCLC) have high risk for depressive symptoms and major depressive disorder (MDD); however, those with epidermal growth factor receptor (EGFR) mutations may have decreased risk. The biological underpinning of this relationship is unknown. We examined differences in depression severity and MDD in patients with newly diagnosed stage IV NSCLC based on...

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Identifiers

PMID: 28712427
DOI: 10.1016/j.jpsychores.2017.05.009

Genes

EGFR
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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