Article
Relationship between SPOP mutation and breast cancer in Chinese population.
Genetics and molecular research : GMR - 16 Oct 2015
Khan M A, Zhu L, Tania M, Xiao X L, Fu J J
Abstract excerpt
SPOP protein has been found to have ubiquitin ligase activity. Mutations in SPOP gene have been recently reported in some cancers such as prostate, gastric, colorectal cancer. We investigated SPOP DNA mutation in tumor tissues collected from 70 Chinese female breast cancer patients in Southwestern China by DNA sequencing. The results did not show mutation in our tissue samples, indicating that a mutation in the...
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