Article
Mutations predisposing to breast cancer in 12 candidate genes in breast cancer patients from Poland.
Clinical genetics - 1 Oct 2015
Cybulski C, Lubiński J, Wokołorczyk D, Kuźniak W, Kashyap A, Sopik V, Huzarski T, Gronwald J, Byrski T, Szwiec M, Jakubowska A, Górski B, Dębniak T, Narod S A, Akbari M R
Abstract excerpt
A number of genes other than BRCA1 and BRCA2 have been associated with breast cancer predisposition, and extended genetic testing panels have been proposed. It is of interest to establish the full spectrum of deleterious mutations in women with familial breast cancer.We performed whole-exome sequencing of 144 women with familial breast cancer and negative for 11 Polish founder mutations in BRCA1, CHEK2 and NBS1,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.