Triple-Negative versus Non-Triple-Negative Breast Cancers in High-Risk Women: Phenotype Features and Survival from the HIBCRIT-1 MRI-Including Screening Study.

doi:10.1158/1078-0432.CCR-15-0459

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Article

Triple-Negative versus Non-Triple-Negative Breast Cancers in High-Risk Women: Phenotype Features and Survival from the HIBCRIT-1 MRI-Including Screening Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2016

Podo Franca, Santoro Filippo, Di Leo Giovanni, Manoukian Siranoush, de Giacomi Clelia, Corcione Stefano, Cortesi Laura, Carbonaro Luca A, Trimboli Rubina M, Cilotti Anna, Preda Lorenzo, Bonanni Bernardo, Pensabene Matilde, Martincich Laura, Savarese Antonella, Contegiacomo Alma, Sardanelli Francesco

Abstract excerpt

PURPOSE: To compare phenotype features and survival of triple-negative breast cancers (TNBC) versus non-TNBCs detected during a multimodal annual screening of high-risk women. EXPERIMENTAL DESIGN: Analysis of data from asymptomatic high-risk women diagnosed with invasive breast cancer during the HIBCRIT-1 study with median 9.7-year follow-up. RESULTS: Of 501 enrolled women with BRCA1/2 mutation or strong family...

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PMID: 26503945
DOI: 10.1158/1078-0432.CCR-15-0459

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BRCA1
BRCA2

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