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Survival benefit in women with BRCA1 mutation or familial risk in the MRI screening study (MRISC).

International journal of cancer - 1 Oct 2015

Saadatmand Sepideh, Obdeijn Inge-Marie, Rutgers Emiel J, Oosterwijk Jan C, Tollenaar Rob A, Woldringh Gwendolyn H, Bergers Elisabeth, Verhoef Cornelis, Heijnsdijk Eveline A, Hooning Maartje J, de Koning Harry J, Tilanus-Linthorst Madeleine M

Abstract excerpt

Adding MRI to annual mammography screening improves early breast cancer detection in women with familial risk or BRCA1/2 mutation, but breast cancer specific metastasis free survival (MFS) remains unknown. We compared MFS of patients from the largest prospective MRI Screening Study (MRISC) with 1:1 matched controls. Controls, unscreened if<50 years, and screened with biennial mammography if ≥50 years, were...

Topics

Adult
Aged
Breast Neoplasms
Case-Control Studies
Female
Genes, BRCA1
Genetic Predisposition to Disease
Humans
Magnetic Resonance Imaging
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Netherlands

Prospective Studies

Source

Identifiers

PMID: 25820931
DOI: 10.1002/ijc.29534

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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