Article
Compromised alveolar bone cells in a patient with dentinogenesis imperfecta caused by DSPP mutation.
Clinical oral investigations - 1 Jan 2019
Porntaveetus Thantrira, Nowwarote Nunthawan, Osathanon Thanaphum, Theerapanon Thanakorn, Pavasant Prasit, Boonprakong Lawan, Sanon Kittisak, Srisawasdi Sirivimol, Suphapeetiporn Kanya, Shotelersuk Vorasuk
Abstract excerpt
OBJECTIVES: Dentin sialophosphoprotein (DSPP) plays an important role in the mineralization of both dentin and bones. The Dspp null mice developed periodontal diseases. Patients with DSPP mutations have dentinogenesis imperfecta (DGI), but very little is known about their bone characteristics. This study aims to characterize alveolar bone cells of a DGI patient with DSPP mutation. MATERIALS AND METHODS:...
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