Article
Meta-analysis of the association of brain-derived neurotrophic factor Val66Met polymorphism with obsessive-compulsive disorder.
Acta neuropsychiatrica - 1 Dec 2015
Wang Jun, Zhang Fuquan, Zhu Wenxian, Liu Yansong, Zhou Zhenhe
Abstract excerpt
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) plays an important role in neural survival and was proposed to be related to psychiatric disorders. Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia. However, studies...
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