The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD).

doi:10.1002/ajmg.b.30930

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Article

The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD).

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2009

Katerberg Hilga, Lochner Christine, Cath Danielle C, de Jonge Peter, Bochdanovits Zoltán, Moolman-Smook Johanna C, Hemmings Sîan M J, Carey Paul D, Stein Dan J, Sondervan David, Boer Johan A den, van Balkom Anton J L M, Polman Annemiek, Heutink Peter

Abstract excerpt

Evidence suggests that the Val66Met variant of the brain-derived neurotrophic factor (BDNF) gene may play a role in the etiology of Obsessive-Compulsive Disorder (OCD). In this study, the role of the BDNF Val66Met variant in the etiology and the phenotypic expression of OCD is investigated. Associations between the BDNF Val66Met variant and OCD, obsessive-compulsive symptom dimensions, Yale-Brown Obsessive...

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PMID: 19219856
DOI: 10.1002/ajmg.b.30930

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BDNF

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