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Article

Pathogenic aspects and therapeutic avenues of intestinal fibrosis in Crohn's disease.

Clinical science (London, England : 1979) - 1 Dec 2015

Zorzi Francesca, Calabrese Emma, Monteleone Giovanni

Abstract excerpt

In Crohn's disease, one of the two major forms of inflammatory bowel diseases in human beings, persistent and chronic inflammation promotes fibrotic processes thereby facilitating formation of strictures, the most common indication for surgical intervention in this disorder. The pathogenesis of Crohn's disease-associated fibrosis is not fully understood, but variants of genes involved in the recognition of...

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Identifiers

PMID: 26494636
DOI: 10.1042/CS20150472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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