Article
Association study of androgen signaling pathway genes in polycystic ovary syndrome.
Fertility and sterility - 1 Feb 2016
Ketefian Aline, Jones Michelle R, Krauss Ronald M, Chen Yii-Der I, Legro Richard S, Azziz Ricardo, Goodarzi Mark O
Abstract excerpt
OBJECTIVE: To evaluate genes involved in androgen receptor (AR) signaling as candidate genes for polycystic ovary syndrome (PCOS). DESIGN: Two groups of women with PCOS and control women (discovery and replication cohorts), were genotyped for single-nucleotide polymorphisms (SNPs) in eight genes for AR chaperones and co-chaperones: HSPA1A, HSPA8, ST13, STIP1, PTGES3, FKBP4, BAG1, and STUB1. Single-nucleotide...
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