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Article

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome.

PloS one - 1 Jan 2011

Jones Michelle R, Chua Angela, Chen Yii-Der I, Li Xiaohui, Krauss Ronald M, Rotter Jerome I, Legro Richard S, Azziz Ricardo, Goodarzi Mark O

Abstract excerpt

Novel pathways in polycystic ovary syndrome (PCOS) are being identified in gene expression studies in PCOS tissues; such pathways may contain key genes in disease etiology. Previous expression studies identified both dickkopf homolog 1 (DKK1) and DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1) as differentially expressed in PCOS tissue, implicating them as candidates for PCOS susceptibility. To test this, we...

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Source

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Identifiers

PMID: 21611153
DOI: 10.1371/journal.pone.0020120
PMCID: PMC3096662

Genes

DNAJB1
DKK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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