Article
TNF-α/TNFR2 Regulatory Axis Stimulates EphB2-Mediated Neuroregeneration Via Activation of NF-κB.
Journal of cellular physiology - 1 Jun 2016
Pozniak Paul D, Darbinyan Armine, Khalili Kamel
Abstract excerpt
HIV-1 infected individuals are at high risk of developing HIV-associated neurocognitive disorders (HAND) as HIV infection leads to neuronal injury and synaptic loss in the central nervous system (CNS). The neurotoxic effects of HIV-1 are primarily a result of viral replication leading to the production of inflammatory chemokines and cytokines, including TNF-α. Given an important role of TNF-α in regulating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
