Article
Influence of CYP2D6 and β2-adrenergic receptor gene polymorphisms on the hemodynamic response to propranolol in Chinese Han patients with cirrhosis.
Journal of gastroenterology and hepatology - 1 Apr 2016
Zhang Feng, Duan Xuhong, Zhang Ming, Li Zhenlei, He Qibin, Wang Yi, Miao Chengcheng, Zhong Wenqi, Zou Xiaoping, Zhuge Yuzheng
Abstract excerpt
BACKGROUND AND AIM: Propranolol is widely used to prevent gastroesophageal variceal bleeding; however, some patients could not benefit from propranolol. This study is to evaluate the relationship between CYP2D6 and β2-adrenergic receptor (β2-AR) gene polymorphisms and the hemodynamic response to propranolol in Chinese Han patients. METHODS: The clinical data of patients with gastroesophageal varices undergoing...
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