Influences of LIN-12/Notch and POP-1/TCF on the Robustness of Ventral Uterine Cell Fate Specification in Caenorhabditis elegans Gonadogenesis.

doi:10.1534/g3.115.022608

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Article

Influences of LIN-12/Notch and POP-1/TCF on the Robustness of Ventral Uterine Cell Fate Specification in Caenorhabditis elegans Gonadogenesis.

G3 (Bethesda, Md.) - 19 Oct 2015

Sallee Maria D, Aydin Taner, Greenwald Iva

Abstract excerpt

The prospective ventral uterus of the hermaphrodite gonad primordium consists of two pairs of sister cells, with each pair consisting of a proximal "α" cell and a distal "β" cell. All four cells initially are competent to become the anchor cell (AC), a unique cell type that acts as the organizer of subsequent uterine and vulval development. However, the β cells soon lose this competence and always become ventral...

Topics

Alleles
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
DNA-Binding Proteins
Female
Gene Expression
Genes, Reporter
Gonads
High Mobility Group Proteins
Insulin-Secreting Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Biological

Mutation

Organogenesis

Phenotype

Receptors, Notch

TCF Transcription Factors

Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 26483009
DOI: 10.1534/g3.115.022608
PMCID: PMC4683648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26483009-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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